Kugulitsa Factory Tetracaine Hydrochloride CAS 136-47-0 Tetracaine HCl

Malangizo: hcl sungunuka m'madzi, maziko osasungunuka m'madzi.(Tetracaine Base imasungunuka m'madzi otentha!)

Kodi Tetracaine Hydrochloride ndi chiyani?

Tetracaine HCl imapangidwa kuchokera ku 4-butylaminobenzoic acid.Ethyl ester imapangidwa kudzera mu acid-catalyzed esterification reaction.Base-catalyzed transesterification imatheka pophika ethyl ester ya 4-butylaminobenzoic acid ndi owonjezera 2-dimethylaminoethanol pamaso pa sodium ethoxid pang'ono.

Tetracaine (INN, yomwe imadziwikanso kuti amethocaine; dzina la malonda Pontocaine. Ametop ndi Dicaine) ndi mankhwala osokoneza bongo amphamvu apagulu a ester.Amagwiritsidwa ntchito kwambiri pamutu pa ophthalmology komanso ngati antipruritic, ndipo amagwiritsidwa ntchito popanga opaleshoni ya msana.
Mu kafukufuku wamankhwala, tetracaine amagwiritsidwa ntchito kusintha njira zotulutsira kashiamu (ryanodine receptors) zomwe zimayang'anira kutulutsidwa kwa calcium m'masitolo opezeka m'magazi.Tetracaine ndi allosteric blocker ya ntchito ya njira.Pazochepa kwambiri, tetracaine imayambitsa kulepheretsa koyambirira kwa zochitika zodziwikiratu za kutulutsidwa kwa kashiamu, pamene pazigawo zazikulu, tetracaine midadada imamasulidwa kwathunthu.
Kodi pali kusiyana kotani pakati pa mphamvu ya anesthetic ya tetracaine hydrochloride powder ndi lidocaine, procaine?
Mankhwala oletsa ululu m'deralo: Tetracaine base>tetracaine hcl>lidocaine>lidcaine hcl> benzocaine> procaine>procaine hcl, koma zotsatira zofanana zidzawonjezeka.