Umzi-mveliso uthengisa iTetracaine Hydrochloride CAS 136-47-0 Tetracaine HCl

Iingcebiso: i-hcl enyibilikayo emanzini, isiseko esinganyibilikiyo emanzini.(Isiseko seTetracaine siyanyibilika emanzini ashushu!)

Yintoni iTetracaine Hydrochloride?

I-Tetracaine HCl yenziwe kwi-4-butylaminobenzoic acid.I-ethyl ester yenziwa nge-acid-catalyzed esterification reaction.I-Base-catalyzed transesterification iphunyezwa ngokubilisa i-ethyl ester ye-4-butylaminobenzoic acid kunye ne-2-dimethylaminoethanol engaphezulu kwe-2-dimethylaminoethanol phambi kwenani elincinci le-sodium ethoxid.

I-Tetracaine (INN, ekwaziwa njenge-amethocaine; igama lokurhweba i-Pontocaine. I-Ametop kunye ne-Dicaine) sisizobisi esinamandla sendawo yeqela le-ester.Isetyenziswa kakhulu kwi-ophthalmology kunye ne-antipruritic, kwaye isetyenziswe kwi-anesthesia yomgogodla.
Kuphando lwe-biomedical, i-tetracaine isetyenziselwa ukuguqula umsebenzi weendlela zokukhululwa kwe-calcium (i-ryanodine receptors) ezilawula ukukhutshwa kwe-calcium kwiivenkile ze-intracellular.I-Tetracaine yi-blocker ye-allosteric yomsebenzi wesiteshi.Kwiindawo eziphantsi, i-tetracaine ibangela ukuvinjelwa kokuqala kweziganeko zokukhutshwa kwe-calcium ngokukhawuleza, ngelixa kwiindawo eziphezulu, iibhloko ze-tetracaine zikhulula ngokupheleleyo.
Uthini umahluko phakathi kwe-anesthetic intensity ye-tetracaine hydrochloride powder kunye ne-lidocaine, i-procaine?
I-anesthetics yendawo: Isiseko se-Tetracaine> i-tetracaine hcl> i-lidocaine> i-lidcaine hcl> i-benzocaine> i-procaine> i-procaine hcl, kodwa imiphumo ehambelana nayo iya kwanda.